Yin Hang1, Dong Bo2, Yang Feng2, Yuan Puwei2, Kang Wulin2, Liu Deyu2
1The First School of Clinical Medicine, Shaanxi University of Traditional Chinese Medicine, Xianyang, Shaanxi, 712046, China
2Department of Osteopathology, Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine, Xianyang 712000, China
To summarize the clinical features of a case of sporadic amyotrophic lateral sclerosis (SALS), improve the ability of early diagnosis and differential diagnosis, and summarize the treatment experience. [Methods] The clinical data of a case of sporadic amyotrophic lateral sclerosis (SALS) in our hospital were analyzed, and the diagnosis and treatment experience was summarized according to its history, clinical manifestations, and imaging and electromyogram manifestations, combined with relevant literature reports at home and abroad. [Results] After comprehensive treatment, the patient was in stable condition and discharged without any progress. After discharge, the patient continued to follow up. Although the systemic symptoms progressed, the degree was slight. [Conclusion] The etiology and pathogenesis of SALS are very complex, and the disease continues to progress. At present, there is no particularly effective treatment for this kind of disease. Comprehensive treatment can be adopted to control the development of the disease, so as to better improve the quality of life and survival rate of patients.
Amyotrophic lateral sclerosis; Loose hair; Case analysis; combined treatment
Yin Hang, Dong Bo, Yang Feng, Yuan Puwei, Kang Wulin, Liu Deyu. Sporadic amyotrophic lateral sclerosis: a case report and literature review. International Journal of Frontiers in Medicine (2022), Vol. 4, Issue 7: 13-15. https://doi.org/10.25236/IJFM.2022.040703.
 Zhoumeihong, Xurenhui, Fang Pu, et al Clinical manifestation analysis and literature review of 50 cases of sporadic amyotrophic lateral sclerosis [J] Practical clinical medicine, 2007 (06): 16-18
 Liumingsheng, Cuiliying. Research Progress on motor neuron excitability in amyotrophic lateral
sclerosis [j/ol]. Chinese Science: Life Science: 1-4[2021-08-17 14:49]
 LIU W, LI X, SUN Y, et al. Genotype-phenotype correlations in a chinese population with familial amyotrophic lateral sclerosis [J]. Neurological research, 2021, 1-11.
 Ma Teng, Huang Yinlan, Li Ling. Research Progress on etiology and pathogenesis of amyotrophic lateral sclerosis in traditional Chinese and Western medicine [J]. Shi Zhen, Guoyi, Guoyao, 2015,26 (12): 2990-2992.
 ZHANG J, QIU W, HU F, et al. The rs2619566, rs10260404, and rs79609816 Polymorphisms Are Associated With Sporadic Amyotrophic Lateral Sclerosis in Individuals of Han Ancestry From Mainland China [J]. Frontiers in genetics, 2021, 12(679204.
 COYNE A, BASKERVILLE V, ZAEPFEL B, et al. Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS [J]. Science translational medicine, 2021, 13(604)
 FIFITA J, CHAN MOI FAT S, MCCANN E, et al. Genetic Analysis of Tryptophan Metabolism Genes in Sporadic Amyotrophic Lateral Sclerosis [J]. Frontiers in immunology, 2021, 12(701550.
 Dang Jingxia. Clinical features, diagnosis and treatment of amyotrophic lateral sclerosis [J]. Journal of Xi'an Jiaotong University (Medical Edition), 2018,39 (05): 613-619.
 WALLER R, WYLES M, HEATH P, et al. Small RNA Sequencing of Sporadic Amyotrophic Lateral Sclerosis Cerebrospinal Fluid Reveals Differentially Expressed miRNAs Related to Neural and Glial Activity [J]. Frontiers in neuroscience, 2017, 11(731.
 Wei Yan, Zhu Jiuyu, Kou Jiyou, Sun Yuanzheng. 17 cases of amyotrophic lateral sclerosis treated by Electroacupuncture at Jiaji point combined with moxibustion [J]. China acupuncture, 2018,38 (06): 613-615.10.13703/j.0255-2930.2018.06.011.