Jianhui Wang1, Fanhua Meng2
1Neuromedical Center, South China Hospital Affiliated to Shenzhen University, Shenzhen 518111, Guangdong, China
2Stroke Ward, Beihua University Affiliated Hospital, Jilin, 132011, Jilin, China
Reducing the adverse stress response of patients in the perioperative period is the most basic principle of accelerated rehabilitation. It is well known that surgery will prompt the body to produce a corresponding stress response, thereby stimulating the body to release various hormones and inflammatory mediators, resulting in enhanced catabolism, which is not conducive to the healing of incisions and wounds. However, a series of measures of accelerated recovery in the perioperative period are precisely to reduce the occurrence of adverse stress reactions in patients. The purpose of this study is to systematically evaluate the efficacy and safety of the concept of fast recovery surgery in the operation of gynecological malignant tumors with the help of Meta analysis method, and to evaluate the efficacy and safety of fast recovery surgery concept in gynecological malignant tumor surgery. The use in tumor patients provides a basis for clinical surgeons to explore the best perioperative treatment plan. The experimental results show that the heart rate wake-up period of patients who use butorphanol 2 mg and dexmedetomidine 0.5 μg is shorter. For dezocine 10 mg and dexmedetomidine 0.5 μg, the heart rate wake-up time of group A was 68.82 minutes and 71.23 minutes, respectively. Butorphanol 2 mg and dexmedetomidine 0.5 μg were used to accelerate the recovery of patients with gynecological malignant tumors. have a certain effect.
Accelerated Recovery, Wound Healing, Malignant Tumor, Meta Analysis
Jianhui Wang, Fanhua Meng. Study of Butorphanol, Dezocine and Dexmedetomidine in the Field of Accelerated Recovery of Gynecological Malignancies. International Journal of Frontiers in Medicine (2022), Vol. 4, Issue 8: 5-9. https://doi.org/10.25236/IJFM.2022.040802.
 Guo Hao, Li Zhishan, Wang Zhi, et al. Clinical effect of dexmedetomidine combined with sufentanil in percutaneous transforaminal surgery. Chinese Medicine, 2019, 14(7): 1054 -1057.
 Ye Xianrui, Li Jin, Li Wulin. Application of dexmedetomidine in orthopedic vertebroplasty. Jiangxi Medicine, 2019, 54(3): 270-271.
 Eisenach, James C. Alpha-2 agonists and analgesia. Expert Opinion on Investigational Drugs, 1994,3(10):1005-1010.
 Ebert TJ, Hall JE, Barney JA, et al. The effects of increasing plasma concentrations of dexmedetomidine in humans. Anesthesiology, 2000, 93(2): 382-394.
 Yin Yue, Zhao Guoqing, Li Kai. Advances in clinical application of butorphanol. China Laboratory Diagnostics, 2019, 23(6): 1101-1103.
 Meng Zhixiu, Huang Bing. Pharmacological effects of butorphanol and its application in postoperative analgesia. Medical Review, 2008, 14(15):2341-2343.
 Galloway FM, Varma S .Double-blind comparison of intravenous doses of dezocine, butorphanol, and placebo for relief of postoperative pain. Anesth Analg, 1986, 65(3):283-287.
 Fan Jie. Effects of butorphanol preemptive analgesia on blood gas indexes and stress response in patients undergoing laparoscopic cholecystectomy. China Rational Drug Use Exploration. 2019, 16(5):94-97.
 Xu Jianguo, Luo Ailun, Wu Xinmin, et al. Expert advice on postoperative analgesia with dezocine. Journal of Clinical Anesthesiology, 2013, 29(9): 921-922.
 Xi Wenjuan, Zhao Jianqiu, Wang Jing, et al. Research progress of dezocine for postoperative analgesia. Medical Review, 2015, 21(15): 2811-2813.
 Zhang Zhenya, Pan Lijie, Wang Jianfang, et al. Analgesic effect of dezocine on patients after laparoscopic appendectomy. China Journal of New Drugs, 2019, 28(22): 2746-2748.
 Zhou Xianjin, Xia Zhongyuan. Meta-analysis of the efficacy and safety of dezocine for preoperative analgesia. China Medical Herald, 2014, 10(27): 4-7.