International Journal of Frontiers in Medicine, 2022, 4(8); doi: 10.25236/IJFM.2022.040812.
Liang Zhuang1, Dong Bo2, Yang Lei1, Yuan Puwei2, Li Xun2, Yang Feng2, Liu Deyu2, Kang Wulin2, Wang Zhankui2, Yang Zhao1
1Shaanxi University of Traditional Chinese Medicine, Xianyang, Shaanxi, 712046, China
2Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine, Xianyang, Shaanxi 712000, China
Background: At present, the treatment of Ankylosing spondylitis (AS) with Traditional Chinese medicine has attracted wide attention. There are different reports on the efficacy of Biqi capsule in the treatment of AS. Therefore, this study systematically evaluated the effectiveness of Biqi capsule or combined conventional treatment of AS, BASDAI, BASFI, C-reactive protein (CRP), and the occurrence of adverse reactions for meta-analysis. [Methods]: Randomized controlled trials of Biqi capsules or combined conventional treatment of AS were searched in 8 databases including CNKI, VIP, Wanfang Data, CBM, PubMed, Web of Science, Embase and Cochrane Library from July 2022. The effect rate of BIqi capsule on AS, BASDAI score, BASFI score, CRP and the occurrence of adverse reactions were evaluated by random effect model system. [Results]: Seven studies were included with 582 participants, 291 in the treatment group and 291 in the control group. Compared with the control group, the effective rate of BIqi capsule or combined conventional treatment of AS drugs was significantly improved, BASDAI score and BASFI score were significantly reduced, and CRPand adverse reactions had no significant difference. [Conclusion]: Biqi capsule is safe and effective in the treatment of AS, and can significantly improve the activity function.
Biqi capsule; Ankylosing spondylitis; AS. Meta analysis; Efficient
Liang Zhuang, Dong Bo, Yang Lei, Yuan Puwei, Li Xun, Yang Feng, Liu Deyu, Kang Wulin, Wang Zhankui, Yang Zhao. Systematic evaluation of efficacy and safety of Biqi capsule in the treatment of ankylosing spondylitis. International Journal of Frontiers in Medicine (2022), Vol. 4, Issue 8: 72-78. https://doi.org/10.25236/IJFM.2022.040812.
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