Welcome to Francis Academic Press

International Journal of Frontiers in Medicine, 2022, 4(9); doi: 10.25236/IJFM.2022.040906.

Clinical Application of Asarum in Children with Pulmonary Diseases


Shuzhen Liu1, Yaxiong Guo2, Ye Zhang3

Corresponding Author:
Yaxiong Guo

1Shaanxi University of Traditional Chinese Medicine, Xianyang, China

2Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine, Xianyang, China

3Northwest Women and Children Hospital, Xi’an, China


Purpose: Studies on Asarum are more biased to adult internal medicine and miscellaneous diseases, pediatrics is rare, This study systematically summarized Asarum toxicity and its clinical application in pediatric pulmonary diseases. Method: Refer to the relevant literature, combined with the physiological and pathological characteristics of children, explore the reduction of Asarum toxicity, and explain the clinical experience of Professor Guo Yaxiong using Asarum to treat pediatric pulmonary diseases. Result:" Asarum is not more than a coin dagger", refers to the powder, only use, in decoction to add and diminish the disease. Conclusion: Traditional Chinese medicine dialectical first promote Yin and Yang, paying attention to the role of Yang; Asarum, spicy and warm, good for the treatment of pediatric pulmonary diseases, achieved good effect. 


Asarum, Toxicity, Pediatric Pulmonary diseases, Clinical application

Cite This Paper

Shuzhen Liu, Yaxiong Guo, Ye Zhang. Clinical Application of Asarum in Children with Pulmonary Diseases . International Journal of Frontiers in Medicine (2022), Vol. 4, Issue 9: 28-32. https://doi.org/10.25236/IJFM.2022.040906.


[1] Zong Shiyu, Liu Yang, Sun Tingting, Zhang Hong, Wang Chunliu, Zhi Wenbing, Li Ye. Progress in Asarumity and its control methods [J]. Chinese Pharmacist, 2020,23 (05): 942-945.

[2] Zhao Jiachen, Wang Yihan, Weng Qianqian, Jin Yan, Zhang Wei, Peng Huasheng, Li Bing, Cai Qiujie, Yang Hongjun, Zhang Huamin, Zhan Zhilai. The herbal research of Asarum in the classical famous formula [J]. Chinese Modern Traditional Chinese Medicine, 2020,22 (08): 1303-1319 + 1330.

[3] Xu Shunan, Niu Zhanbing. Shennong Materia Medica Classic [M]. Shijiazhuang: Hebei Science and Technology Press, 1994 (3): 20.

[4] Dong Liangjie, Wang Shuming. Asarum dosage study [J]. Chinese Journal of Basic Medicine of Traditional Chinese Medicine, 2000,6 (4): 39.

[5] Nie Anzheng, Zhao Xuerui, Zhu Chunsheng, Zhang Bing. Asarum drug evolution and thoughts on rational drug use [J]. Chinese herbal medicine, 2018,49 (23): 5719-5723.

[6] Jin M, Kijima A, Suzuki Y, et al. A comprehensive toxicity study of safrole using a medium-term animal model with delta rats [J]. Toxicology, 2011, 290(2/3): 312-321. 

[7] Cheng Jimin, Zhang Dechang. An examination of the dosage of Asarum. Jiangsu Pharmacy and Clinical Research, 2000, (1): 36.

[8] Liang Qi, Xie Ming. TCM toxicity and its connotation are differentiated and analyzed [J]. Journal of Integrated Traditional Chinese and Western Medicine, 2009,7 (2): 101.

[9] Yang Jingjing, Cao Zhuoqing, Ma Jing, Chen Yanqing, Qin Yali, Jia Yuejin. Exploring and analyzing the Clinical application and contraindication of Asarum [J]. Traditional Chinese Medicine Research, 2018,31 (04): 1-2.

[10] Xue Yan, Tong Xianghui, Wang Feng, et al. UPLC-UV mensurate the aristolochic acid A of Asarum in the aboveground and underground areas [J]. Journal of Pharmacy, 2008,43 (2): 221-223.

[11] Shen Zhihua, Zuo Zhiqin, Chen Weiran, Jiang Xuezhen, Lan Ruiqun. Analysis "Asarum is no more than one coin dagger" [J]. Jiangxi Traditional Chinese Medicine, 2020,51 (12): 13-15. 

[12] Liu Yajing. Study of the processing drugs and detoxification of aristolochic acid in Asarum [D]. Jilin Agricultural University, 2008:44-46.

[13] Jia Bo, Cao Lanxiu, Deng Zhongjia, et al. Experimental study on Asarum toxicity and the compatibility of medicines detoxification [J]. Journal of Jiangxi College of Traditional Chinese Medicine, 2006,18 (2): 50-51.

[14] Yan Heguo, Yang Bo, Hou Jianting, et al. The clear-up doubts of"Asarum is no more than one coin dagger" [J]. Traditional Chinese Medicine Bulletin, 2016,15 (6): 44-45.

[15] Li Yang. Analysis of the rule of Asarum drug use based on the correlation of "toxicity-effect-certificate" [J]. Clinical Journal of Traditional Chinese Medicine, 2018,30 (09): 1627-1629.

[16] Hu Zixian (BENCHERIF,JORDAN). History of Asarum's clinical dosage and its toxicity study [D]. Beijing University of Traditional Chinese Medicine, 2019.