Lupatadine has dual antagonistic effect, which can play an obvious antagonistic effect on histamine H1 receptor and platelet activating factor receptor. It is a new type of anti allergic drug, which can effectively inhibit inflammation in all stages of allergic reaction. This drug has the characteristics of rapid onset and long-lasting effect. It is recommended to take orally once a day in clinical application. Clinical studies have shown that oral low-dose of lupatadine can effectively relieve the symptoms of seasonal and perennial allergic rhinitis. With the deepening of relevant research in recent years, it has been found that lupatadine has good therapeutic effect on skin diseases such as chronic urticaria, and patients have better tolerance to this drug. In this paper, through the relevant literature review, summarize and analyze the new progress of pharmacodynamics and application of lupatadine, mainly from the drug effect and clinical application.

Honggao Duan. New Progress in Pharmacodynamics and Application of Lupatadine. International Journal of Frontiers in Medicine (2022), Vol. 4, Issue 10: 1-5. https://doi.org/10.25236/IJFM.2022.041001.

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