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Academic Journal of Medicine & Health Sciences, 2022, 3(2); doi: 10.25236/AJMHS.2022.030209.

Mapping Aging Biomarkers and Pathways Using Proteomics


Tingyi Cui1, Ruofei Zhang2

Corresponding Author:
Tingyi Cui

1The High School Affiliated to Renmin University of China, Beijing, China

2Beijing 21st Century International School, Beijing, China


Aging is the leading factor in many diseases. During aging, a lot of proteins and pathways are dramatically changed, which may serve as potential aging biomarkers and targets for anti-aging drug development. In this review, we summarize the current progress in aging-related biomarkers and pathways that have been identified by proteomics. We find that many proteins in metabolism pathways are involved in aging process, which have a positive- or a negative-correlation. Changes in many   have strong relationship with aging, including mTOR pathway, pro-inflammatory pathway, insulin/insulin-like signaling pathway, mitochondrial function pathway.


Aging, Protein, Proteomics, Biomarker

Cite This Paper

Tingyi Cui, Ruofei Zhang. Mapping Aging Biomarkers and Pathways Using Proteomics. Academic Journal of Medicine & Health Sciences (2022) Vol. 3, Issue 2: 52-57. https://doi.org/10.25236/AJMHS.2022.030209.


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