Academic Journal of Medicine & Health Sciences, 2022, 3(3); doi: 10.25236/AJMHS.2022.030302.
Wu Jinyue, Qiu Penghui, Du Xu
Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712000, China
This paper illustrates the effects of acupuncture on synaptic plasticity through three aspects: plasticity of synaptic structures, function and expression of synaptic plasticity-related proteins, and summarizes the relevant mechanisms of acupuncture on synaptic plasticity, aiming to improve the mechanisms of acupuncture on neurological diseases in the field of neuroplasticity, and provide a more accurate, scientific and better basis for clinical treatment.
Acupuncture; Synaptic plasticity; The ability to learn
Wu Jinyue, Qiu Penghui, Du Xu. Advances in the mechanism of action of acupuncture in regulating synaptic plasticity. Academic Journal of Medicine & Health Sciences (2022) Vol. 3, Issue 3: 7-12. https://doi.org/10.25236/AJMHS.2022.030302.
[1] Feng Min. Effects of acupuncture on synaptic plasticity of hippocampal neurons in AD model mice and study on AMPA receptor mechanism [D].2012 Chengdu University of Traditional Chinese Medicine Doctoral Dissertation, 2012:2-9.
[2] Lin Yao. Effects of moxibustion on synaptic plasticity of hippocampal neurons in rapidly aging mice [D]. Beijing University of Traditional Chinese Medicine, 2019.
[3] ZHANG Hao. Modulation of synaptic plasticity in hippocampus and prefrontal cortex by electroacupuncture in depressed rats [D]. Guangzhou University of Traditional Chinese Medicine, 2019.
[4] GUO Bin. Study on the regulation mechanism of electroacupuncture Quchi-Yanglingquan on cerebral synaptic plasticity in rats with limb spasm after stroke [D]. Hunan, Hunan University of Traditional Chinese Medicine, 2020.
[5] Song Changming, Huang Jia, Lin Bingbing, et al. Effects of electroacupuncture on learning and memory ability and synaptic ultrastructure of hippocampal CA1 region in rats with cerebral ischemia-reperfusion [J]. Chin J Rehabilitation Theory and Practice, 2017,23(07):750-755.
[6] Tang Yong. Cellular and molecular mechanisms of electroacupuncture promoting synaptic plasticity of dopamine neurons in Parkinson's disease mice [D]. Chengdu University of Traditional Chinese Medicine, 2004.
[7] Chen Jianguo. Synaptic plasticity and its function [J]. Journal of Xianning College (Medical Edition),2004(03):153-156.
[8] Zhang Xiaoshu. Effect of acupuncture on excitatory synaptic transmission of SAMP8 hippocampal neurons in AD model mice [D]. Chengdu University of Traditional Chinese Medicine, 2013.
[9] Zhang Yuhao. Study on the mechanism of electroacupuncture in improving learning and memory function of vascular dementia based on hippocampal synaptic transmission efficiency and plasticity [D]. Fujian University of Traditional Chinese Medicine, 2020.
[10] Feng Kehui. Inhibitory effect of electroacupuncture on long-term potentiation (LTP) of C-fiber evoked potentials in a rat model of neuropathic pain [D]. Nanjing University of Traditional Chinese Medicine, 2010.
[11] Zheng Mengyu. Effects of acupuncture on expression levels of GAP-43 and Caspase-3 in rats with cerebral ischemia-reperfusion [D]. Liaoning University of Chinese Medicine,2020.
[12] Li Ying. Effects of different frequencies of electrical stimulation on the expression of SYP and GAP-43 in cerebral cortex of rats with cerebral infarction [D]. Heilongjiang University of Chinese Medicine, 2016.
[13] Wang Xiaolan. Effect of moxibustion pretreatment on the expression of NGF and BDNF in hippocampal CA1 region of Alzheimer's disease model rats [D]. Hubei University of Traditional Chinese Medicine, 2012.
[14] Lin Yao, Zuo Yingzhu, Ha Lue, et al. Effect of moxibustion on expression of synaptic plasticity related proteins in hippocampus of rapidly aging mice [J]. World Journal of Chinese Medicine, 2019,14(05):1149-1152.
[15] Zhang Kangkang. Effects of different frequencies of electricity on synaptophysin and PSD-95 in AD rats [D]. Hubei University of Traditional Chinese Medicine,2016.
[16] Xiang Dulian. Effect of electroacupuncture on behavior and expression of PSD-95 and SYP in hippocampus of AD mice [D]. Beijing University of Traditional Chinese Medicine,2019.
[17] Xie Zhengrong, Xiao D0u, Tang Yani, et al. Effects of electroacupuncture at pericardial meridian points on the expression of synaptophysin and postsynaptic dense-95 in serum and brain tissue of rats with MCAO [J]. Journal of Chinese Medicine Information,2021,28(01):81-85.