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Frontiers in Sport Research, 2022, 4(7); doi: 10.25236/FSR.2022.040703.

Advances in the Effects of Aerobic Exercise on Mitochondrial Function and Anti-aging of Muscles


Zhenlei Lv

Corresponding Author:
Zhenlei Lv

College of Health Sciences, Hainan Vocational University of Science and Technology, Haikou, China


The aging of skeletal muscle is associated with the change of mitochondrial function. In increasingly aging society, exercise has been an important factor for health. Recent research showed that the decrease of proteins related to mitochondrial dynamics and the loss of skeletal muscle mass were only associated with protein OPA1. Aerobic exercise could increase the level of OPA1 in skeletal muscle, increase the amount of mitochondria and the secretion of cytokines in skeletal muscle, inhibit the generation of reactive oxygen species (ROS), thus regulate donwstream effectors, inhibit skeletal muscle atrophy and influence systemic metabolism and aging.


aerobic exercise, skeletal muscle, signing, mitochondrial dynamics

Cite This Paper

Zhenlei Lv. Advances in the Effects of Aerobic Exercise on Mitochondrial Function and Anti-aging of Muscles. Frontiers in Sport Research (2022) Vol. 4, Issue 7: 14-18. https://doi.org/10.25236/FSR.2022.040703.


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