Xiaoyao Powder is composed of Radix Bupleuri, Radix Angelicae Sinensis, Radix Paeoniae Alba, Radix Glycyrrhizae, Rhizoma Atractylodis Macrocephalae, Poria, Ginger and Mentha haplocalyx. It has the effects of soothing liver and relieving depression, nourishing blood and invigorating spleen. It is a classic prescription for harmonizing liver and spleen and is widely used in clinical practice. Modern clinical studies have confirmed that this prescription has a good therapeutic effect on post-stroke depression, dementia, headache and other brain diseases, but its components are numerous, the mechanism of action is complex, and the research results are scattered. Therefore, the author focuses on the main treatment of brain diseases. Combined with the results of modern experimental research, the mechanism of action of the active components related to single herbs in the prescription and the clinical application of the compound application of the compound induction and collation, the mechanism of action and experimental research status of the prescription were further clarified, providing valuable reference for the majority of physicians in clinical application.

Tao Peng, Xilei Li, Yongmei Yan. Advances in clinical and experimental research on xiaoyao powder in brain disorders. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 1: 7-13. https://doi.org/10.25236/IJFM.2023.050102.

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