The decline of ovarian reserve function refers to the decline of ovarian reproductive function and endocrine function, which is reflected by the decline of the quantity and quality of ovarian follicles. The occurrence of this disease directly leads to the decline of female fertility and the lack of sex hormones, and further can develop into premature ovarian failure. The effect of traditional Chinese medicine in the treatment of this disease is quite significant. We will make a brief introduction to the understanding and treatment of this disease in traditional Chinese medicine, so that our later research can be more specific and serve the majority of patients.

Juanjuan Zhang, Xiaoping Cui. Clinical study of traditional Chinese medicine in the treatment of decreased ovarian reserve function. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 2: 31-36. https://doi.org/10.25236/IJFM.2023.050206.

[1] Menopause Group of Chinese Society of Obstetrics and Gynecology. Expert consensus on hormone replacement therapy for premature ovarian insufficiency [J]. Chin J Obstetrics and Gynecology, 2016, 51 (12) :881-886.

[2] Xu Xiaofeng, Tan Yong, Chen Xuanyi. Chinese Medicine Information Journal, 2009, 16 (12): 492-497. (in Chinese)

[3] Han Lanxiang, Du Juan, Guo Yangzhi. Cong Huifang's experience in treating premature ovarian failure. Sichuan TCM,2012,30 (2) :16-17.

[4] Liu Wei-ping, LI Peipei. Chinese Journal of Traditional Chinese Medicine Information, 2015, 22 (10) :97-99.

[5] Zhao Hongli, Zhang Qin, Ma Jing. Experience of He Jialin in the treatment of premature ovarian failure [J]. Zhejiang Journal of Traditional Chinese Medicine, 2012, 47(4):240-241.

[6] Yuan Ailing, Wang Fang, Yang Xianhai. Li Zhiyuan's experience in the treatment of premature ovarian failure from the liver [J]. Seeking Medical Advice, 2012, 10(7):82-83.

[7] Chen Jing, Wang Chunyan. Professor Hu Guo-hua's experience in the treatment of premature ovarian failure and low ovarian reserve function. World Journal of Integrated Chinese and Western Medicine, 2013, 8(10):988-990.

[8] Ma Huirong, Du Huilan, Song Cuimiao, Yang Xiufang, Cao Gang, Li Qingxue. Effects of Bushen Tiaojing Decoction on oxidative damage, antioxidant capacity and ovarian estrogen level in anovulation rats induced by androgen [J]. Chinese Materia Medica Pharmacology & Clinic, 2004, 20(5):34-36.

[9] Zhang Y. The clinical study of Bushen Huoxue prescription regulating oxidative stress to improve ovarian reserve function in patients with kidney deficiency and blood stasis [D]. Nanjing University of Chinese Medicine, 2020.

[10] Chen Yanxia. Study on the mechanism of Bushen Huo decoction regulating PI3K and Nrf2 signaling pathway to protect low ovarian reserve function [D]. China Academy of Chinese Medical Sciences, 2020.

[11] Wang Qian, LU Ge, Xie Zijing, et al. Effect of moxibustion on Nrf2/HO-1 signaling pathway in rats with decreased ovarian reserve [J]. Chinese Acupuncture and Moxibustion, 2021, 41(1):6.

[12] CAI Liang, Li Li, Zhao Yilin, et al. Effect of Bushen Jianpi acupuncture on ovulation induction with antagonist protocol in infertility patients undergoing IVF-ET treatment [J]. Shanghai Journal of Acupuncture and Moxibustion, 2021, 40(1):5.

[13] Wang F H ,  Tan Y ,  Yin Y Y , et al. Effects of Ziyin Buyang Sequential Formula combined antagonist on the outcome of poor ovarian response in vitro fertilization[J]. China Journal of Traditional Chinese Medicine and Pharmacy, 2019.