The oral microbiome is highly diverse, with approximately 700 microorganisms, including bacteria, fungi, and viruses, and is one of the five major bacterial reservoirs (intestinal, oral, cutaneous, nasal, and genitourinary tracts), making the oral microbiota of children unique and easily accessible compared to other body sites. Several studies have demonstrated that the oral microbiota of children are closely associated with systemic diseases and can be used as an early warning marker of systemic health. In this article, we review several common systemic diseases in children based on recent research advances.

Yanling Wang, Boqi Li, Yishan Liu. Early warning role of oral microorganisms in systemic systemic diseases in children. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 3: 62-66. https://doi.org/10.25236/IJFM.2023.050311.

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