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International Journal of Frontiers in Medicine, 2023, 5(3); doi: 10.25236/IJFM.2023.050312.

New Developments in the Mechanism of Action of Pomegranate Peel Polyphenols


Yierfan·Nuermaimaiti1, Gulinuer·Awuti2

Corresponding Author:

1Department of Periodontal, the First Affiliated Hospital of Xinjiang Medical University (Affiliated Stomatological Hospital), Urumqi, Xinjiang Uygur Autonomous Region Institute of Stomatology, Urumqi, China

2Department of Periodontal, the First Affiliated Hospital of Xinjiang Medical University (Affiliated Stomatological Hospital), Urumqi, Xinjiang Uygur Autonomous Region Institute of Stomatology, Urumqi, China


Pomegranate Peel Polyphenols are a kind of polyphenolic hydroxyl compounds mainly found in pomegranate peel, whose components include nine compounds including amphiregulin, gallic acid, ellagic acid, epicatechin, kaempferol, caffeic acid and quercetin. The results of numerous studies show that pomegranate peel polyphenols have various biological functions such as antioxidant, antibacterial, anti-inflammatory and anti-tumor. And in recent years, the application of pomegranate peel polyphenols in oral cavity, especially in the treatment of periodontitis, has become a research hotspot. Therefore, this paper reviews the research on the function and application value of pomegranate peel polyphenols in the treatment of systemic and periodontitis by domestic and foreign scholars in recent years, which provides some reference value for the further development and utilization of pomegranate peel polyphenols.


Pomegranate peel polyphenols; Antioxidant; Anti-inflammatory; Antibacterial; Periodontitis

Cite This Paper

Yierfan·Nuermaimaiti, Gulinuer·Awuti. New Developments in the Mechanism of Action of Pomegranate Peel Polyphenols. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 3: 67-71. https://doi.org/10.25236/IJFM.2023.050312.


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