Glioma is the most common primary intracranial tumour and is characterised by high rates of disability, mortality and recurrence. Despite standard treatments such as surgery and adjuvant post-operative radiotherapy, the overall survival of gliomas remains low due to the presence of the blood-brain barrier and resistance to chemotherapeutic agents. Eukaryotic translation initiation factor 3 (EIF3) is involved in the genetic regulation of a variety of tumourigenesis, development and prognosis. In this review, we have reviewed the recent literature on the regulation of EIF3 expression in glioma and discussed the role of some EIF3 subunits in glioma.

Lili Tang, Huanyu Zhao, Haicheng Xia. Research progress of Eukaryon translation initiation factor 3 in Glioma. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 3: 88-93. https://doi.org/10.25236/IJFM.2023.050316.

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