Objective: To analyze the expression and significance of TMEFF2 gene methylation in bladder cancer. Methods: The promoter region methylation level of the MEFF 2 gene was analyzed by applying the expression database and gene methylation.64 urine samples were detected by demethylated drug-nitrogen-2 deoxycytidine to observe the changes of cell invasion and apoptotic valence, and its application value in bladder cancer was analyzed by applying high expression of TMEFF2 gene. Results: Drug treatment of bladder cancer cells showed that the appreciation and migration of bladder cancer were inhibited, but the number of apoptosis increased. Conclusion: TMEFF2 gene promoter methylation is one of the markers of bladder cancer and plays an important role in the diagnosis of bladder cancer.

Xiaoqing Zheng, Hao Zheng, Xi Chu, Chuna Zheng. Expression of TMEFF2 gene and significance of initiation methylation in bladder cancer. Frontiers in Medical Science Research (2023) Vol. 5, Issue 4: 62-66. https://doi.org/10.25236/FMSR.2023.050411.

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