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Frontiers in Medical Science Research, 2023, 5(4); doi: 10.25236/FMSR.2023.050414.

Pharmaceutical Analysis of Nifedipine Combined with Benazepril in the Treatment of Senile Hypertension

Author(s)

Honggao Duan

Corresponding Author:
Honggao Duan
Affiliation(s)

School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Benxi, Liaoning, 117004, China

Abstract

Objective: To analyze the pharmaceutical effect of nifedipine combined with benazepril in the treatment of senile hypertension. Methods: A total of 70 elderly patients with hypertension from January 2021 to January 2022 were randomly divided into two groups, 35 patients in each group. The patients in the control group were treated with nifedipine, while the patients in the observation group were given benazepril. The time of lowering systolic and diastolic blood pressure to normal, the monitoring values of systolic and diastolic blood pressure before and after treatment, the total effective rate and adverse reactions were compared between the two groups. Results: The time of lowering systolic and diastolic blood pressure to normal in the observation group was shorter than that in the control group. After treatment, the monitoring values of systolic and diastolic blood pressure were lower than those in the control group, and the total effective rate was higher than that in the control group, P<0.05. There was no significant difference in adverse reactions between the two groups (P>0.05). Conclusion: Nifedipine combined with Benazepril is effective in the treatment of senile hypertension.

Keywords

Nifedipine; Benazepril; Senile hypertension; Pharmaceutical action

Cite This Paper

Honggao Duan. Pharmaceutical Analysis of Nifedipine Combined with Benazepril in the Treatment of Senile Hypertension. Frontiers in Medical Science Research (2023) Vol. 5, Issue 4: 80-84. https://doi.org/10.25236/FMSR.2023.050414.

References

[1] Shang Jianhua. Observation on the efficacy and safety of benazepril combined with metoprolol in the treatment of senile essential hypertension with heart failure [J]. Guizhou Medicine, 2022, 46(06): 930-931.

[2] Zhang Lifeng. Observation on the effect of metoprolol combined with benazepril in the treatment of senile hypertension with heart failure and the level of cardiac function [J]. Famous doctor, 2022, (09): 186-188.

[3] Yu Xiangzhi. To observe the clinical effect of Benazepril combined with metoprolol tartrate in the treatment of elderly patients with essential hypertension complicated with heart failure [J]. Smart Health, 2022, 8(07):92-94+104.

[4] Tao Shipeng. Clinical efficacy of benazepril combined with metoprolol in the treatment of senile essential hypertension complicated with heart failure [J]. guide of china medicine, 2022,20(05):53-56.

[5] Huang Chenbin, Zhang Yinghui, Chen Yangbao. Clinical effect of metoprolol combined with benazepril on elderly patients with essential hypertension complicated with heart failure [J]. Journal of Clinical Rational Drug Use, 2022, 15(02):49-52.

[6] Sungsana W, Nakaranurack C, Weeraphon B, et al. Telepharmacy during home isolation: drug-related problems and pharmaceutical care in COVID-19 patients receiving antiviral therapy in Thailand[J]. Journal of Pharmaceutical Policy and Practice, 2023, 16(1).

[7] Liu Xiaofei. Efficacy analysis of benazepril combined with furosemide in the treatment of elderly patients with essential hypertension and heart failure [J]. Inner Mongolia Medical Journal, 2021, 53(12): 1462-1464+1467.

[8] Xie Lifang. Gastrodin injection combined with Benazepril in the treatment of elderly patients with essential hypertension [J]. Clinical Practice of Integrated Traditional Chinese and Western Medicine, 2021, 21(23):124-125.

[9] Liu Yingli, Liu Yadong, Cai Yong, Shao Guoxi. Effects of Benazepril combined with Levamlodipine besylate on vascular endothelial function and lipid peroxidation in elderly hypertensive nephropathy patients [J]. China Journal of Gerontology, 2021, 41(23):5236-5239.

[10] Wu Lu, Chen Guang. Effect of Fufang Yangxue Ningfang on blood pressure variability in elderly hypertensive patients [J]. Shenzhen Journal of Integrated Traditional Chinese and Western Medicine, 2021, 31(22):66-68.