Welcome to Francis Academic Press

Academic Journal of Materials & Chemistry, 2023, 4(3); doi: 10.25236/AJMC.2023.040302.

Development of Rare and Endangered Medicinal Material Resources in Southwest China—A Case Study of Bioactivity of Active Compounds from Several Species of Blumea Balsamifera Plants


Pei Zhang1, Nan Wu2, Pengzhi Xiang1

Corresponding Author:
Pei Zhang

1School of Chemical Engineering, Yunnan Open University, Kunming, China

2School of Medicine, Yunnan College of Business Management, Kunming, China


The rare and endangered medicinal materials in Southwest China are the treasures of medical resources in China, among which Blumea balsamifera is the most valuable. In this paper, the economic and social development and the status quo of rare and endangered medicinal materials in southwest China were briefly described, and several common Blumea balsamifera plants and their pharmacological characteristics were analyzed. This paper mainly introduces the main research methods and techniques used in the extraction and separation of active components from Blumea balsamifera plants, and analyzes the chemical constituents of Blumea balsamifera plants. By analyzing the chemical active components (including hair oil, flavonoids, terpenoids, phenylpropanoids, steroids, etc.) in Blumea balsamifera, it was found that the volatile oil, flavonoids and sesquiterpenoids have high medicinal value, which is worth further research and exploration. Due to the author's limited academic ability, there are inevitably some shortcomings in this paper.


Blumea balsamifera plants, Compound composition, Bioactivity study

Cite This Paper

Pei Zhang, Nan Wu, Pengzhi Xiang. Development of Rare and Endangered Medicinal Material Resources in Southwest China—A Case Study of Bioactivity of Active Compounds from Several Species of Blumea Balsamifera Plants. Academic Journal of Materials & Chemistry (2023) Vol. 4, Issue 3: 15-23. https://doi.org/10.25236/AJMC.2023.040302.


[1] Palorini R. DeRasmo D. Gaviraghi M. SalaDanna L. Signorile A. Cirulli C. Chiaradonna F. Alberghina L. Papa S. Oncogenic K-ras expression is associated with derangement of the cAMP/PKA pathway and forskolin-reversible alterations of mitochondrial dynamics and respiration [J]. Oncogene, 2013, 32(3): 352-362. 

[2] Beijing Sihuan Pharmaceutical Co., Ltd., Hainan Sihuan Pharmaceutical Co., Ltd. Composition of cyclic adenosine monophosphate and polyvinylpyrrolidone and its preparation method: Beijing, CN200910009084.4 [P]. 2010-06-23.

[3] Huang Limei, Zhu Jianliang, Sun Min. Research progress of mammalian adenylyl cyclase subtypes [J]. International Journal of Pathological Science and Clinic, 2011, 31(2): 161-166.

[4] Qian X. Gu L. Ning H. Zhang Y. Hsueh E. C. Fu M. Hu X. Wei L. Hoft D. F. Liu J. Increased Th17 cells in the tumor microenvironment is mediated by IL-23 via tumor-secreted prostaglandin E2 [J]. Journal of immunology, 2013, 190(11): 5894-5902. 

[5] Yang Weimin, Chen Zhihe, Wang Decheng. Research progress of forskolin and its analogues against glaucoma [J]. Ophthalmology Research, 2000, 18(4): 382-384.

[6] Yang Weimin, Li Xinhua, Chen Zhihe, Nie Linghui, Wang Boling, Shen Zhiqiang. Forskolin analogs stimulate adenylate cyclase and inhibit rabbit ocular hypertension [J]. Ophthalmology Research, 2001, 19(1): 1-4.

[7] Pharmacopoeia Association of the Ministry of Health of the People's Republic of China. Drug Standards (Prescriptions of Traditional Chinese Medicine) Volume 19 [S]. Beijing: People's Medical Publishing House, 1998.

[8] Editorial Committee of "Chinese Materia Medica" of State Administration of Traditional Chinese Medicine. Chinese Materia Medica [M]. Shanghai: Shanghai Science and Technology Press, 1999.7, 739-742.

[9] Yuan Yuan, Pang Yuxin, Wang Wenquan, Zhang Yingbo, Yu Jingbo. Investigation of the plant resources of the genus Ainaem in China [J]. Journal of Tropical Biology 2011, 2(1): 78-82.

[10] Uddin S. J. Grice I. D. Tiralongo E. Cytotoxic effects of Bangladeshi medicinal plant extracts. Evidence-based complementary and alternative medicine: eCAM2011, 2011, 578092. Available from: http: //www. hindawi. com/journals/ecam/2011/578092/ref/

[11] Chiang L. C. Cheng H. Y. Chen C. C. Lin C. C. Invitroanti-leukemic and antiviral activities of traditionally used medicinal plants in Taiwan [J]. The American journal of Chinese medicine, 2004, 32(5): 695-701. 

[12] Bheemasankara Rao, C. Namosiva Rao, T. Muralikrishna, B. Flavonoids from Blumealacera [J]. Plantamedica, 1977, 31(3): 235-237. 

[13] DeBoer H. J. Cotingting C. Medicinal plants for women's healthcare in southeast Asia: ameta-analysis of their traditional use, chemical constituents, and pharmacology [J]. Journal of ethnopharmacology, 2014, 151(2): 747-767. 

[14] Saifudin A. Tanaka K. Kadota S. Tezuka Y. Chemical constituents of Blumea balsamifera of Indonesia and their protein tyrosine phosphatase1 Binhibitory activity [J]. Natural product communications, 2012, 7(7): 815-818.