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Academic Journal of Materials & Chemistry, 2023, 4(3); doi: 10.25236/AJMC.2023.040303.

Recent progress in biomedical materials modified by polydopamine


Fengjiao Cui, Tingting Yang

Corresponding Author:
Tingting Yang

School of Materials Science and Engineering, Jiamusi University, Jiamusi, Heilongjiang, China


Dopamine (DA), which not only contains catechols, but also includes amino substances. Because DOPA derivative is dopamine, it's essentially the same as DOPA. According to the study of related experts, such as Lee, DA will self-react in the alkaline aerobic humid environment, and PDA nanofilms containing catechol units will be generated on the surface of the substance. The preliminary work showed that polydopamine (PDA) showed excellent advantages in adsorption and bio-compatibility in vivo. In addition, because of its excellent chemical properties, PDA can be used as a "platform" for "secondary modification", grafting a variety of functional small molecules onto the matrix, so as to improve the matrix's osteogenic, antibacterial properties. This paper briefly introduces the research progress of PDA in medical materials and other aspects in order to lay a foundation for PDA to be used more in medical materials research and development.


Polydopamine; Modified organism; Applied research

Cite This Paper

Fengjiao Cui, Tingting Yang. Recent progress in biomedical materials modified by polydopamine. Academic Journal of Materials & Chemistry (2023) Vol. 4, Issue 3: 24-27. https://doi.org/10.25236/AJMC.2023.040303.


[1] Wang Lu. (2021). Titanium scaffolds modified with Tacrolimus hollow polydopamine nanoparticles promote the repair of mandibular defects through FAK/ERK signaling pathway. Published doctoral dissertation, Jilin University, Changchun, Jilin.

[2] Song Yu, Yu Qiuhua, Zhang Yu, Yang Zhongxue, Hou Yudong. (2018). Study on Surface modification of titanium and antibacterial properties of polyamide amide. Journal of Binzhou Medical College, (03), 190-193.

[3] Xu Qing. (2021). Study on preparation, antibacterial and regenerative repair of Bioactive ceramic composites. Published doctoral dissertation, University of Chinese Academy of Sciences (Shanghai Institute of Ceramics, Chinese Academy of Sciences), Shanghai. 

[4] He Lin, Wu Xi, He Song, Yang Sen. (2021). Hydrophilicity and cell adhesion of hydroxyapatite bioceramics coated with polydopamine. Chinese Journal of Tissue Engineering, (22), 3540-3544.

[5] He Lin, Wu Xi, He Song, Yang Sen. (2020). Adhesion, proliferation and osteogenic differentiation of human apillary stem cells on hydroxyapatite and polydopamine-hydroxyapatite [J]. Journal of Stomatological Research, (06), 523-527.

[6] Cheng Xuedan. (2022). Preparation and properties of polydopamine composite antibacterial materials. Published master's thesis, Henan University, Kaifeng, Henan.

[7] Ma Ruiting. (2021). Preparation and application of mesoporous polydopamine nanoparticles. Published master's thesis, Southwest Jiaotong University, Chengdu, Sichuan.

[8] Wan Ailan, Shen Xinyan, Wang Xiaoxiao, Zhao Shuqiang. (2023). Preparation of Graphene/pyrrole conductive Fabric Modified with Polydopamine and its Sensing Response Characteristics. Acta Textile Sinica, (01), 156-163.