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Frontiers in Medical Science Research, 2023, 5(5); doi: 10.25236/FMSR.2023.050514.

Exploring the Combination Characteristics and Mechanism of Kidney Tonifying Effects of Kidney Qi Pill and Right Return Pill Based on the Theory of "Tonifying and Diarrhea"


Yanan Zhou, Cong’e Tan

Corresponding Author:
Cong’e Tan

Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi, China


Kidney Qi Pill is from Zhang Zhongjing's Jinkui Yaolve in the Han Dynasty, while Right Return Pill is from Zhang Jingyue's "JingYue QuanShu" in the Ming Dynasty, although the two sides were created in different dynasties, they are both kidney tonic formulas and are still used today. Drugs such as " three tonics " and "three diarrheas" and various drugs such as "less fire and more anger" in kidney qi pills can achieve tonify the kidney qi, while Right Return Pill is based on the Kidney-Qi Pill by deleting the "three tonics" and retaining the "three diarrhoeas". Both of them have the effect of warming the kidney yang, but Kidney Qi Pill aims to warm the kidney yang and transform the kidney qi, while Right Return Pill fills the kidney essence and helps the kidney yang. Its mechanism of action is the same and different, and at the same time, the "three tonics" are used to "seek yang in the yin", and the difference is the "three diarrhea" drugs and filling in the fine matching and trade-offs of the boutique. This paper aims to compare and analyze the characteristics of the combination of kidney qi pill and Right Return pill and modern molecular mechanism. In order to provide reference for the advantages of these two directions to study the drug and compatibility mechanism.


Kidney Qi Pill; Right Return Pill; Tonics and diarrhoea; Formulation and combination; Mechanism of action

Cite This Paper

Yanan Zhou, Cong’e Tan. Exploring the Combination Characteristics and Mechanism of Kidney Tonifying Effects of Kidney Qi Pill and Right Return Pill Based on the Theory of "Tonifying and Diarrhea". Frontiers in Medical Science Research (2023) Vol. 5, Issue 5: 94-98. https://doi.org/10.25236/FMSR.2023.050514.


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