Modern medicine believes that intestinal flora affects the development of polycystic ovary syndrome through five pathways: brain-gut axis, chronic inflammatory state, intestinal mucosal permeability, short-chain fatty acid metabolism, and bile metabolism. According to TCM, the key pathogenesis of polycystic ovary syndrome is spleen deficiency and phlegm obstruction, and it is mostly treated from the spleen. The intestinal flora and the spleen have many physiopathological correlations, and prescriptions for strengthening the spleen have a regulatory effect on the number and structure of intestinal flora, which provides a basis for treating polycystic ovary syndrome from the spleen and broadens the thinking of clinical treatment of polycystic ovary syndrome.

Xiaofan Li, Xia Liu, Xinchun Xiao. Exploring Spleen-Based Treatment Based on the Correlation between Intestinal Flora and Spleen Polycystic Ovary Syndrome. Frontiers in Medical Science Research (2023) Vol. 5, Issue 5: 99-104. https://doi.org/10.25236/FMSR.2023.050515.

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