Objective: To analyze platelet count after resection of liver primary carcinoma and its clinical significance. Methods: This study is a retrospective analysis of the clinical data of 128 patients with liver primary carcinoma who underwent hepatectomy in the Department of Hepatobiliary Surgery, Medical School the First Affiliated Hospital of  School of Medicine, Shihezi University from August 20 to August 2019.According to platelet count levels (PLT),  the patients were grouped on the first day after surgery, platelet counts <100×109/L were divided into low platelet groups, normal groups at 100-300×109/L, and correlation between platelet count and postoperative liver failure was analyzed for a diagnostic value. Results: Among the 128 patients, 35 of them were grouped as with low platelet counts on the first day after surgery, and the other 93 patients were normal. There were 20 cases of liver failure within six months after the patient underwent surgery.In the single factor analysis of liver failure, the age of  liver failure group, the PLT value one day after surgery and the preoperative liver function B grade were higher than the non-hepatic failure group, the difference was statistically significant (P>0.05); In the multivariate analysis, both the PLT count on the first postoperative day and the preoperative liver function grading are independent risk factors for the complications of hepatic failure after hepatectomy. The PLT count on the first day after surgery has a good predictive value for hepatic failure after liver carcenoma complications. The ROC curve was drawn. When the Jordan count was 0.431, the sensitivity and specificity were 0.60 and 0.83 respectively. The area AUC=0.753 (0.651 to 0.854). Conclusion: Age and postoperative PLT count and preoperative liver function were important pathogenic factors for liver failure after hepatectomy. Platelet count has diagnostic value for predicting liver failure after resection of primary liver carcinoma.

Hou Jiaying, Li lin, Liu Qinghua. Recovery of platelet count in patients with liver primary carcinoma after hepatectomy and its clinical significance. Frontiers in Medical Science Research (2019) Vol. 1 Issue 4: 35-43. https://doi.org/10.25236/FMSR.2019.010406.

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