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Academic Journal of Humanities & Social Sciences, 2020, 3(1); doi: 10.25236/AJHSS.2020.030111.

Advances in the study of hyperuricemia and chronic kidney disease

Author(s)

Yunli Gui, Xiaorong Bao*

Corresponding Author:
Xiaorong Bao
Affiliation(s)

Jinshan Hospital of Fudan University, Shanghai 201508, China.
*Corresponding author e-mail:wangyu-syd@sina.com

Abstract

At present, hyperuricemia is becoming an increasingly serious problem after hypertension, hyperglycemia, and hyperlipidemia. It has also become a hot topic in recent years. Uric acid passes through the glomerular filtration and is then reabsorbed or excreted by the URAT1 transporter in the renal tubules. Hyperuricemia affects the functional status of the glomerulus and renal tubules, and high uric acid indirectly leads to renal insufficiency through vascular sclerosis. This article reviews the development of chronic kidney disease caused by high uric acid, including glomerular damage, renal tubule damage and vascular sclerosis.

Keywords

Uric acid, Hyperuricemia, Chronic kidney disease, Renal tubule, Glomerular, Vascular sclerosis.

Cite This Paper

Yunli Gui, Xiaorong Bao. Advances in the study of hyperuricemia and chronic kidney disease. Academic Journal of Humanities & Social Sciences (2020) Vol. 3, Issue 1: 98-103. https://doi.org/10.25236/AJHSS.2020.030111.

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