Welcome to Francis Academic Press

Frontiers in Medical Science Research, 2024, 6(2); doi: 10.25236/FMSR.2024.060212.

A Meta-analysis of Risk Factors for Irritable Bowel Syndrome in China

Author(s)

Qian Tang1, Haonan Zhao1, Hui Ding2

Corresponding Author:
Hui Ding
Affiliation(s)

1Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China

2Shaanxi Academy of Traditional Chinese Medicine, Xi'an, Shaanxi, 710003, China

Abstract

In order to systematically evaluate the risk factors for irritable bowel syndrome, We searched CNKI, Wanfang, Weipu and PubMed databases for risk factors for irritable bowel syndrome in China, Newcastle-Ottawa Scale (NOS) used the most comprehensive data collection based on relevant case-control trials, combined with inclusion and exclusion criteria to evaluate the quality of the extracted literature, included the literature with a score of ≥7, and finally meta-analyzed using RevMan 5.4. In the end, 15 articles met the inclusion criteria, with a cumulative number of 5171 cases and 3088 controls, respectively. It was concluded that history of alcoholism, spicy food, seafood, irregular diet, gastrointestinal infection, drug history, anxiety (long-term tension), sleep disorder (insomnia), personality sensitivity (introversion), family history of IBS, smoking, psychiatric (psycho-depressive factors), and family and marital events were independent risk factors for IBS, and controlling the above factors could effectively reduce the risk of IBS patients.

Keywords

Irritable bowel syndrome; IBS; risk factors; Case-control studies

Cite This Paper

Qian Tang, Haonan Zhao, Hui Ding. A Meta-analysis of Risk Factors for Irritable Bowel Syndrome in China. Frontiers in Medical Science Research (2024), Vol. 6, Issue 2: 68-76. https://doi.org/10.25236/FMSR.2024.060212.

References

[1] Gastrointestinal Functional Diseases Collaborative Group, Chinese Society of Gastroenterology, Chinese Society of Gastroenterology, Gastrointestinal Dynamics Group, Chinese Society of Gastroenterology. 2020 Chinese Expert Consensus on Irritable Bowel Syndrome [J]. Chinese Journal of Digestion, 2020, 40(12):803-818.

[2] Zhang Mingming, Jiang Min. Advances in the pathogenesis of irritable bowel syndrome [J]. World Chinese Journal of Digestology, 2009, 17(24):2484-2490.

[3] Zhang Lu, Duan Liping, Liu Yixuan, et al. A meta-analysis of the prevalence and risk factors of irritable bowel syndrome in Chinese community [J]. Chinese Journal of Internal Medicine, 2014, 53(12):969-975.

[4] Greenland S. Quantitative methods in the review of epidemiologic literature [J]. Epidemiologic reviews, 1987, 9(1):1-30.

[5] Chen Zongxian, Zheng Huicai. A case-control study on risk factors of irritable bowel syndrome [J]. Occupation and Health, 2014, 30(05):656-657.

[6] Cui Lihong. Analysis of related factors and evaluation of diagnostic criteria for irritable bowel syndrome [D].Chinese People's Liberation Army Medical College, 2013.

[7] Guo Hong, Yao Ping. Risk factors for constipation-predominant irritable bowel syndrome:an analysis of 100 cases [J]. World Chinese Journal of Digestology, 2011, 19(14):1524-1528.

[8] Wei Xiaojing, Wang Peirong. Analysis of depression and anxiety status of patients with different subtypes of irritable bowel syndrome and its influencing factors [J]. China Modern Doctor, 2014, 52(28):134-137.

[9] Zhao Wenju. Clinical study on risk factors for the pathogenesis of irritable bowel syndrome [D]. Wannan Medical College, 2021.

[10] Zheng Jie, Dang Tong. The effect of lifestyle and eating habits on irritable bowel syndrome [J]. Chinese Journal of Clinical New Medicine, 2016, 9(04):301-304.

[11] Wang Siling, Yuan Hao, Tao Leting, Chen Haixing. Investigation on the correlation between diarrheal irritable bowel syndrome and dietary factors in Qingdao [J]. Qingdao Medicine and Health, 2017, 49(02):84-87.

[12] Qi Lingzhi, Song Xiangzhen. Analysis of influencing factors in 50 cases of irritable bowel syndrome [J]. Jilin Medical Journal, 2016, 37(12):2914-2916.

[13] Yao Lujing. Analysis on pathogenesis of 150 cases with irritable bowel syndrome [J]. Modern Medical Journal, 2012, 40(05):560-562.

[14] Lv Hongjie. Risk factors investigation study on irritable bowel syndrome [J]. Chinese Journal of Hospital Statistics, 2014(1):22-24.

[15] Jin Jianjun, Wang Suling, Jia Jianchen, et al. Study on pathogenic factors for irritable bowel syndrome [J]. Clinical Focus, 2003(22):1287-1288.

[16] Lin Hong. Investigation on food intake of high FODMAPs and other related factors in patients with irritable bowel syndrome [D]. Fujian Medical University, 2016.

[17] Liu Chang, Chen Weigang. Analysis of lifestyle in patients with various subtype irritable bowel syndrome [J]. Jilin Medical Journal, 2017, 38(10):1836-1838.

[18] Luo Chang, Lv Shangze, Bai Tao, et al. Differences in lifestyle factors between functional constipation and constipation-predominant irritable bowel syndrome [J]. Chinese Journal of Digestion, 2015, 35(07):460-464.

[19] Xu Xiaoxing, Li Dingguo, Zhu Guanghui, et al. Time cluster and symptom character of 402 outpatients with irritable bowel syndrome [J]. World Chinese Journal of Digestology, 2003(08):1234-1236.

[20] Xiong Lishou, Chen Minhu, Chen Huixin, et al. Epidemiological Study on Irritable Bowel Syndrome in Community Population of Guangdong Province [J]. National Medical Journal of China, 2004(04):18-21.

[21] Bode C, Bode J C. Alcohol's role in gastrointestinal tract disorders [J]. Alcohol health and research world, 1997, 21(1):76-83.

[22] Lundström Olof, Manjer Jonas, Ohlsson Bodil, et al. Smoking is associated with several functional gastrointestinal symptoms [J]. Scandinavian journal of gastroenterology, 2016, 51(8):914-922.

[23] Niu Qinghui, Jiang Yueping, Zhang Cuiping, et al. Evaluation of Clinical Characteristics of Irritable Bowel Syndrome in Coastal Areas of Qingdao [J]. Chinese Journal of Gastroenterology, 2010, 15(02):109-111.

[24] Liu Chunbin, Liang Gu, Zheng Qinfang, et al. Prevalence of and risk factors for irritable bowel syndrome in community residents in Nanning [J]. World Chinese Journal of Digestology, 2014, 22(34):5365-5370.

[25] Chen Feixue. Study on the role of anxiety-induced BDNF-CRF brain-gut interaction in the pathogenesis of IBS [D]. Shandong University, 2021.

[26] Bellini Massimo, Gemignani Angelo, Gambaccini Dario, et al. Evaluation of latent links between irritable bowel syndrome and sleep quality [J]. World journal of gastroenterology, 2011, 17(46):5089-5096.

[27] Chang Yuanyuan, Wang Bangmao, Wang Yuming, et al. Psychological alterations and autonomic nervous dysfunction in patients with irritable bowel syndrome [J]. World Chinese Journal of Digestology, 2011, 19(03):309-313.

[28] Zuo Rong, Wang Qiaomin, Zhang Xu, et al. The relationship between ultrastructure of colonic mucosa and intestinal mucosal barrier dysfunction in post infectious irritable bowel syndrome [J]. Journal of Bengbu Medical College, 2012, 37(02):171-172+175.

[29] Bellini Massimo, Gambaccini Dario, Stasi Cristina, et al. Irritable bowel syndrome: a disease still searching for pathogenesis, diagnosis and therapy [J]. World journal of gastroenterology, 2014, 20(27):8807-8820.