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Frontiers in Medical Science Research, 2024, 6(7); doi: 10.25236/FMSR.2024.060710.

Relationship between calcium-phosphorus product and coronary artery calcification

Author(s)

Ya Li, Chunlai Zeng

Corresponding Author:
Chunlai Zeng
Affiliation(s)

Wenzhou Medical University Sixth Affiliated Hospital, Wenzhou City, Zhejiang Province, 323000, China

Abstract

Abnormal calcium and phosphorus metabolism is closely related to coronary artery calcification (CAC), but the relationship between calcium-phosphorus product(Ca-P product) and coronary artery calcification in other population is not completely clear. A retrospective analysis was performed on 199 patients who had received coronary computed tomography angiography(CCTA). Univariate and multivariate analyses were performed to evaluate the association between Ca-P product and coronary artery calcification. Compared with the non-calcification group, the Ca-P product was significantly increased in the mild and moderate calcification groups, while there was no significant change in the severe calcification group. After excluding severe calcification, logistics regression analysis after adjusting confounding factors indicated that the Ca-P product was positively correlated with CAC>0 (OR1.121,95%CI(1.035, 1.216),P=0.006). In addition, the total CACS and the prevalence of CAC in the high Ca-P product group were significantly higher than those in the low Ca-P product group. In the non-coronary group, the CAC group had a higher Ca-Pproduct than the non-CAC group. Excluding severe calcification patients,Ca-P product is associated with CAC.

Keywords

Ca-P product; Coronary artery calcification; Coronary atherosclerotic heart disease

Cite This Paper

Ya Li, Chunlai Zeng. Relationship between calcium-phosphorus product and coronary artery calcification. Frontiers in Medical Science Research (2024), Vol. 6, Issue 7: 84-89. https://doi.org/10.25236/FMSR.2024.060710.

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