Frontiers in Medical Science Research, 2024, 6(11); doi: 10.25236/FMSR.2024.061103.
Zhang Yaqin1,2, Zhang Qiangqiang1, Yang Jiyuan1, Hu Yan1
1The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei, 434000, China
2School of Clinical Medicine, Yangtze University, Jingzhou, Hubei, 434000, China
Schistosomiasis japonica is a parasitic disease that was once widespread in China, especially in the middle and lower reaches of the Yangtze River. Although it has been properly controlled in China, there are still some areas where schistosomiasis infection still exists. We found that schistosome eggs are not only prone to sedimentation in the liver, ultimately leading to cirrhosis, but also prone to the development of colorectal cancer. Therefore, this article will discuss the mechanism of action, diagnosis, and treatment prognosis of colorectal cancer related to schistosomiasis, summarize the latest research progress, and provide a basis for clinical treatment.
Schistosomiasis; Colorectal cancer; Mechanism of action; Diagnosis; treat
Zhang Yaqin, Zhang Qiangqiang, Yang Jiyuan, Hu Yan. Research on the Application Progress of Schistosomiasis Related Colorectal Cancer. Frontiers in Medical Science Research (2024), Vol. 6, Issue 11: 13-17. https://doi.org/10.25236/FMSR.2024.061103.
[1] SIEGEL R L, MILLER K D, JEMAL A. Cancer statistics, 2019[J]. CA Cancer J Clin, 2023, 69(1): 7-34.
[2] Chen Pu, Yuan Liyue, Lei Yuyang, et al. Analysis of SLC5A1 expression in pancreatic cancer and its potential cancer promoting effect based on TCGA database[J]. Journal of Naval Medicine, 2022, 43(07): 708-714.
[3] BRENNER H, KLOOR M,POX C P. Colorectal cancer[J]. Lancet, 2021, 383(9927):1490-1502.
[4] PLUMMER M, DE MARTEL C, VIGNAT J, et al. Global burden of cancers attributable to infections in 2012: a synthetic analysis[J]. Lancet Glob Health, 2022,4(9):e609-e616.
[5] Wang Meilian, Liu Beixing. Research progress on the characteristics and immunopathological mechanisms of schistosomiasis infection[J]. J Microbiol, 2020,40(03):109-113.
[6] Zhang Lijuan, Xu Zhimin, Qian Yinjun, et al. 2015 National Schistosomiasis Epidemic Report[J]. Chinese Journal of Schistosomiasis Control, 2016,28(06):611-617.
[7] Tong Fei. Schistosomiasis japonica and its comprehensive prevention and control measures[J]. Shandong Animal Husbandry and Veterinary Medicine, 2023,44(04):36-38.
[8] MEDEIROS T B, DOMINGUES A L, LUNA C F, et al. Correlation between platelet count and both liver fibrosis and spleen diameter in patients with schistosomiasis mansoni[J]. Arq Gastroenterol, 2022, 51(1):34-38.
[9] FANG L, YANG Z, ZHANG M, et al. Clinical characteristics and survival analysis of colorectal cancer in China: a retrospective cohort study with 13,328 patients from southern China[J]. Gastroenterol Rep (Oxf), 2021,9(6):571-582.
[10] TORRE L A, BRAY F, SIEGEL R L, et al. Global cancer statistics, 2012[J]. CA Cancer J Clin, 2015,65(2):87-108.
[11] LIANG L, LIANG Y, Li K, et al. A risk-prediction score for colorectal lesions on 12,628 participants at high risk of colorectal cancer[J]. Gastroenterol Rep (Oxf), 2022,10(1):goac2.
[12] VESCHOOR Y L, VAN DE HAA J, VAN DEN BERG J G, et al. Neoadjuvant atezolizumab plus chemotherapy in gastric and gastroesophageal junction adenocarcinoma: the phase 2 PANDA trial[J]. Nat Med, 2024,30(2):519-530.
[13] WANG W, LU K, WANG L, et al. Comparison of non-schistosomal colorectal cancer and schistosomal colorectal cancer[J]. World J Surg Oncol, 2020,18(1):149.
[14] Xiao Ran, Li Fei, Zhou Xianjun. Correlation analysis between chronic schistosomiasis and colorectal cancer[J]. Journal of Clinical Surgery, 2019,27(9):779-781.
[15] SCANU T, SPAAPEN R M, BAKKER J M, et al. Salmonella Manipulation of Host Signaling Pathways Provokes Cellular Transformation Associated with Gallbladder Carcinoma[J]. Cell Host Microbe, 2021,17(6):763-774.
[16] LU R, BOSLAND M, XIA Y, et al. Presence of Salmonella AvrA in colorectal tumor and its precursor lesions in mouse intestine and human specimens[J]. Oncotarget, 2022,8(33):55104-55115.
[17] YANG Q, QIU H, XIE H, et al. A Schistosoma japonicum Infection Promotes the Expansion of Myeloid-Derived Suppressor Cells by Activating the JAK/STAT3 Pathway[J]. J Immunol, 2021, 198(12):4716-4727.
[18] Yang XuoHong, Sun Maoyuan, Xiao Qiang, et al. The effect of ALDH1 on the biological functions of colorectal cancer cells and its mechanism of action in schistosomiasis related colorectal cancer[J]. Clinical Oncology and Rehabilitation in China, 2020,27(02):146-151.
[19] Li Gangqin, Zhang Yuxing, Gong Ligang, et al. Expression of cytochrome P450 Ⅱ E1 in intestinal mucosa of patients with schistosomiasis and colorectal cancer[J]. Journal of Anatomy, 2015, 46(03): 400-404.
[20] LIU W, ZENG H Z, WANG Q M, et al. Schistosomiasis combined with colorectal carcinoma diagnosed based on endoscopic findings and clinicopathological characteristics: a report on 32 cases[J]. Asian Pac J Cancer Prev, 2022,14(8):4839-4842.
[21] ZHANG F, WANG X, ZHU Y, et al. Conjoint analysis of clinical, imaging, and pathological features of schistosomiasis and colorectal cancer[J]. Pathol Oncol Res, 2023,29:1611396.
[22] Zhang Bin, Xiao Xiaowei. Exploration of clinical significance of serum concentration detection of transforming growth factor - α in schistosomiasis colorectal cancer[J]. Grassroots Medicine Forum, 2014, 18(01):20-22.
[23] Yang Jianghua,Du Zhixiang, Xuan Kun,et al. Composition analysis and laboratory examination characteristics of 187 patients with schistosomiasis and colorectal cancer[J]. Research on tumor prevention and treatment, 2019,46(09):811-814.
[24] WU W, FENG A, HUANG Y. Research and control of advanced schistosomiasis japonica in China [J]. Parasitol Res, 2023,114(1):17-27.
[25] YI Z, HONG-GANG J, ZHI-HENG C, et al. Short-Term Efficacy of Laparoscopic Treatment for Colorectal Cancer in Patients with Schistosomiasis Japonica[J]. Gastroenterol Res Pract, 2016,2016: 8357025.
[26] CHENG M, JING H, BU D, et al. The predictive value of CD4, CD8, and C-reactive protein in the prognosis of schistosomal and non-schistosomal colorectal cancer[J]. BMC Gastroenterol, 2023, 23(1): 194.
[27] PAN W, WANG W, HUANG J, et al. The prognostic role of c-MYC amplification in schistosomiasis-associated colorectal cancer[J]. Jpn J Clin Oncol, 2021,50(4):446-455.