The gut microbiota, regarded as the “eighth organ” of the human body, plays a crucial role in maintaining the intestinal barrier function, participating in immune regulation, facilitating substance metabolism and absorption, as well as cholesterol degradation. Colorectal cancer, a common malignant tumor of the digestive tract, has the dysbiosis of the gut microbiota as a significant contributing factor to its development. Through various approaches such as the intake of probiotics, prebiotics, synbiotics, and the implementation of microbiota transplantation, the disruption of the gut microbiota can be rectified, and its balance can be sustained. This offers more alternatives in preventing the incidence of colorectal cancer, retarding tumor progression, reducing postoperative complications of colorectal cancer, enhancing the efficacy of anti-tumor drugs, and mitigating their side effects.

Wei Liu, Zhuocheng You, Ruifeng Yang, Zhigang Xiao. Gut Microbiota Imbalance Recovery in Colorectal Cancer Therapy. Frontiers in Medical Science Research (2025), Vol. 7, Issue 5: 109-115. https://doi.org/10.25236/FMSR.2025.070513.

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