Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder characterized by abdominal pain, bloating, and alterations in bowel habits. Its pathogenesis is multifaceted, and effective therapeutic options remain limited. Acupuncture, as a key component of traditional medicine, has in recent years demonstrated distinct advantages in the management of IBS, with growing support from evidence-based medical research. This review systematically examines four proposed mechanisms through which acupuncture exerts its therapeutic effects: modulation of brain-gut axis(also encompassing the broader microbiota‑gut‑brain axis) function, alleviation of visceral hypersensitivity and pain, regulation of gastrointestinal motility and secretion, and restoration of intestinal flora and mucosal immune homeostasis. Furthermore, based on these mechanistic insights, the article explores the theoretical foundation of acupuncture treatment for IBS from the perspective of traditional Chinese medicine.

Yu Liu, Delin Ren, Yunbo Hao, Shiqian Wen, Yongrui Wang, Yan Zuo. Progress in Mechanism of Acupuncture and Moxibustion for Irritable Bowel Syndrome. Frontiers in Medical Science Research (2026), Vol. 8, Issue 1: 17-23. https://doi.org/10.25236/FMSR.2026.080102.

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