Objective: To investigate the effect of repetitive transcranial magnetic stimulation (rTMS) on the symptoms of amphetamine-dependent patients after withdrawal. Method: 71 patients with amphetamine-dependent patients were randomly divided into study group and control group. The study group received system rTMS. Treatment, the control group received pseudo-stimulation treatment similar to rTMS, a total of 5 times. At baseline and after the first and fifth treatments, the visual analog scale (VAS) and the amphetamine withdrawal symptom assessment scale were used to assess the patient's psychological craving and symptoms after withdrawal. Results: After one magnetic stimulation treatment in the study group and the control group, the scores were lower than the baseline scores (p<0.05). After 5 treatments, the study group scores were lower than the baseline scores (p<0.05), and the control group scores and baseline values were not statistically different. After the fifth magnetic stimulation, the study group's symptom scores, emotional disorder scores, physical symptoms scores, and withdrawal scores of the amphetamine withdrawal symptom scale were lower than the baseline scores. There was no statistical difference between the control group scores and the baseline values. Regression analysis showed that the total score of withdrawal symptoms before and after intervention in the study group was positively correlated with baseline VAS values and duration of drug use. Conclusion: rTMS can significantly improve the symptoms of amphetamine-dependent patients after withdrawal, and it is safe and worth promoting.

Yijin Zheng, Conghui Cheng, Yiwen Hu, shen Jing, Repetitive transcranial magnetic stimulation for symptomatic improvement of amphetamine-dependent patients after withdrawal. Frontiers in Medical Science Research (2019) Vol. 1: 1-13.https://doi.org/10.25236/FMSR.100101.

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