Frontiers in Medical Science Research, 2021, 3(1); doi: 10.25236/FMSR.2021.030111.
Shouyong Xiao1, 3, Siyun Wu2, 3, Sunying Rao1, Zhou Chen1, Cao Run1, Wang Wei1, Qinling Sun1, Cui Xin1, Lianhua Ye1*
1Department of Cardiothoracic surgery, The Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China
2Department of Cardiology, the First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China
3Kunming Medical University, Kunming, Yunnan, China
Contributions: All authors listed had made a great contribution to the work. X-SY, W-SY initially developed the concept and drafted and revised the manuscript. All the authors took responsible to the final manuscript and approved it for publication.
*Correspondence: [email protected]
Background: Thoracic solitary fibrous tumors (TSFT) are a rare disease. We aim to determine the prognostic factors related to survival of TSFT patients through the use of The Surveillance, Epidemiology, and End Results database to analyze demographic and clinical characteristics. This study is intended to determine the prognostic factors associated with TSFT and has clinical value. Patients and Methods: This is a retrospective study of patients who were diagnosed with TSFT in the SEER database from 2001 to 2015. The kaplan-Meier method and Cox regression analysis were used to identify prognostic factors for patient survival. Results: From the SEER database (2001-2015), 227 patients with TSFT were detected. The 5-year survival rate was 82.7%, and the 10-year survival rate was 62.4%. Surgical resection [HR 0.314, 95% CI 0.201-0.491, P <0.001] was just an independent factor in the improvement of patient prognosis. Conclusion: The results of this study indicate that the prognostic factors for TSFT patients are age, grade, surgery, and chemotherapy. Age <65 years old, well-differentiated, surgery instead of chemotherapy is a favorable prognostic factor for survival of TSFT patients.
Solitary fibrous tumor, prognostic factors, surgery, SEER
Shouyong Xiao, Siyun Wu, Sunying Rao, Zhou Chen, Cao Run, Wang Wei, Qinling Sun, Cui Xin, Lianhua Ye. Analysis of prognostic factors and survival of Thoracic solitary fibrous tumors: a SEER population-based study. Frontiers in Medical Science Research (2021) Vol. 3 Issue 1: 64-70. https://doi.org/10.25236/FMSR.2021.030111.
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