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Academic Journal of Engineering and Technology Science, 2019, 2(1); doi: 10.25236/AJETS.020031.

Systematic Analysis of Efficiency and Safety of Dexamethasone and Cimetidine in the Treatment of Gastroenteritis

Author(s)

Jingjing Wanga, Wei Jiangb, Tao Lic and Guozhong Ji*

Corresponding Author:
Guozhong Ji
Affiliation(s)

The Second Affiliated Hospital of Nanjing Medical University, Nanjing 211166, China
*Corresponding author e-mail: jgzzl@163.com, awjj1201@njmu.edu.com, bnjmujiangwei@163.com, c13813453084@163.com

Abstract

The purpose of this study is to determine the efficiancy and safety of two drugs in the treatment of gastroenteritis by META analysis, and to establish a preliminary evaluation system. PubMed (1966-2018.1), CochraneLibrary (1996-2018.1), Embase (1974-2018.1), CNKI (1994-2018.1), VIP (1989-2018.1) and CBM (1978-2018.1). Exclusion criteria and quality was evaluated and data were extracted. Meta analysis was performed using RevMan 5.0 software. A total of 16 RCTs were enrolled. The quality of the study was moderate. A total of 1333 patients with ulcerative colitis were enrolled. Meta-analysis showed that in the total rate, dexamethasone was superior to cimetidine in the treatment of ulcerative colitis. There were 12 RCTs reported adverse reactions, and dexamethasone had fewer adverse reactions. META analysis showed that both efficacy and safety of dexamethasone were better.

Keywords

META analysis, gastroenteritis, cimetidine, dexamethasone​

Cite This Paper

Jingjing Wang, Wei Jiang, Tao Li and Guozhong Ji, Systematic Analysis of Efficiency and Safety of Dexamethasone and Cimetidine in the Treatment of Gastroenteritis. Academic Journal of Engineering and Technology Science (2019) Vol. 2: 184-190. https://doi.org/10.25236/AJETS.020031.

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