Frontiers in Medical Science Research, 2021, 3(6); doi: 10.25236/FMSR.2021.030601.
Kehan Lin1, Hengxi Liu2, Junying Li3, Chenhao Shou4, Yihan Xia5, Ming Chu6, Xi Chen7
1Nanjing Medical University, Nanjing, Jiangsu, China
2University of Washington--Seattle, Seattle, WA, United States
3The Barstow School-Ningbo Campus, Ningbo, Zhejiang, China
4Hangzhou Foreign Languages School, Hangzhou, Zhejiang, China
5Shanghai Pinghe Bilingual School, Shanghai, China
6,7Department of Immunology, School of Basic Medical Sciences, Peking University. NHC Key Laboratory of Medical Immunology (Peking University). Beijing, China.
These authors contributed equally to this work
The Sequencing reads of this study are derived from research shared by Aaron J. Wilk. We conducted a deep analysis of B lymphocyte data. A total of 2126 differentially expressed genes were listed out. Through GO enrichment analysis, 24 clusters related to B lymphocyte functioning were screened out, and genes with significant differential expression were mainly enriched in 10 KEGG signaling pathways related to immune regulatory functions. This suggests that there are differences in the expression of immune regulatory genes in the immune process of B lymphocytes during the Sars-Cov2 infection.
COVID-19, B lymphocytes, expression difference
Kehan Lin, Hengxi Liu, Junying Li, Chenhao Shou, Yihan Xia, Ming Chu, Xi Chen. Differential gene expression in B lymphocyte immune process induced by COVID-19 infection. Frontiers in Medical Science Research (2021) Vol. 3 Issue 6: 1-5. https://doi.org/10.25236/FMSR.2021.030601.
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