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Frontiers in Medical Science Research, 2022, 4(5); doi: 10.25236/FMSR.2022.040510.

Research progress in drug therapy of coronary heart disease and angina pectoris

Author(s)

Jiangmiao Lou

Corresponding Author:
Jiangmiao Lou
Affiliation(s)

Zhuji People's Hospital of Zhejiang Province, Zhuji, China

Abstract

Coronary heart disease angina pectoris is a common symptom of coronary heart disease, which is mainly caused by patients' coronary artery hardening to varying degrees and abnormal blood flow, resulting in sudden intermittent sharp pain in the chest, which has a great impact on the life and health of patients. At present, there are many drugs for the treatment of coronary heart disease and angina pectoris. Western drugs include nitrates, calcium antagonists β Receptor blockers, statins. Traditional Chinese medicine includes drugs for removing blood stasis and excess, drugs for promoting blood circulation and tonifying deficiency, etc. The efficacy and indications of each drug are different. This paper reviews the literature on the drug treatment of coronary heart disease and angina pectoris.

Keywords

coronary heart disease, angina pectoris; medication; Curative effect; progress

Cite This Paper

Jiangmiao Lou. Research progress in drug therapy of coronary heart disease and angina pectoris. Frontiers in Medical Science Research (2022) Vol. 4, Issue 5: 59-63. https://doi.org/10.25236/FMSR.2022.040510.

References

[1] Zhuang Shaoping, Zhu Youfeng, Wei Jianrui. Meta-analysis of therapeutic effect of compound Danshen dripping pills and nitrates on stable angina pectoris of coronary heart disease. International Medical and Health Herald, 2021,27(04):501-508. 

[2] Zhuang Chenlin. Pharmacological action of nitrates and clinical analysis of treating angina pectoris. Chinese and foreign medical treatment, 2019,38(26):127-129. 

[3] Chen Xiaojing. Clinical observation on treatment of unstable angina pectoris with Tongmai Decoction combined with aspirin and nitrates. chinese medicine modern distance education of china, 2020,18(14):123-125. 

[4] Peng Danya. 78 cases of angina pectoris due to coronary heart disease were treated with Wenxin Granule and nitrates. Shaanxi Traditional Chinese Medicine, 2013,34(09):1142-1144.

[5] Sueda S, Izoe Y, Fukuda H. Calcium antagonists did not improve BMIPP cardiac scintigraphy in patients with pure coronary spastic angina. J Am Coll Cardiol, 2005,45(3).

[6] Shozo S, Akira O, Yousuke I, et al. A long-acting calcium antagonist over one year did not improve BMIPP myocardial scintigraphic imagings in patients with pure coronary spastic angina. Ann Nucl Med, 2007,21(2).

[7] Sueda S. Calcium antagonists and vasospastic angina: History and therapeutic changes. Respiration and Circulation, 2005,53(9).

[8] Charlotte N, Mojgan S. Calcium antagonists and their use with older people:In the second of a new series, Charlotte Nicholls and Mojgan Sani discuss the use of calcium antagonists, now widely accepted as a treatment for hypertension and angina. Nurs Older People, 2003,15(9).

[9] Yamagishi M, Ito K, Tsutsui H, et al. Lesion Severity and Hypercholesterolemia Determine Long-Term Prognosis of Vasospastic Angina Treated With Calcium Channel Antagonists. Circ J, 2003,67(12).

[10] Heidenreich P A, McDonald K M, Hastie T, et al. An evaluation of beta-blockers, calcium antagonists, nitrates, and alternative therapies for stable angina. Evidence report/technology assessment (Summary), 1999,(10).

[11] Heidenreich P A, McDonald K M, Hastie T, et al. Meta-analysis of trials comparing beta-blockers, calcium antagonists, and nitrates for stable angina. JAMA, 1999,281(20).

[12] Heidenreich PA, McDonald KM, Hastie T, et al. Meta-analysis of Trials Comparing β-Blockers, Calcium Antagonists, and Nitrates for Stable Angina. JAMA: The Journal of the American Medical Association, 1999,281(20).

[13] Motivala AA, Parikh V, Roe M, et al. Predictors, Trends, and Outcomes (Among Older Patients >= 65 Years of Age) Associated With Beta-Blocker Use in Patients With Stable Angina Undergoing Elective Percutaneous Coronary Intervention Insights From the NCDR Registry. JACC Cardiovasc Interv, 2016,9(16).

[14] Xu Zhiru. Clinical experience of β -blockers in the treatment of unstable angina pectoris. China Continuing Medical Education, 2015,7(05):214-215.

[15] Perondi R, Saino A, Zanchetti A, et al. Coronary vascular reactivity and calcium antagonist therapy in patients with angina. J Cardiovasc Pharmacol, 1994,24 Suppl A.

[16] Yu GN, Ilushina T P, Kolosova K S. The possibilities of using beta-blocker bisoprolol in patients with stable angina with concomitant bronchial asthma. Kardiologiia, 2022,62(1).

[17] Nishinaka Y, Yokota M, Watanabe M, et al. Hemodynamic effects of the calcium channel blocker pranidipine on exercise-induced angina. Int J Clin Pharmacol Ther, 1994,32(10).

[18] Su Dexing. Effect of statins on myocardial ischemia in patients with stable angina pectoris with normal blood lipid. Gansu Science and Technology, 2017, 33(09):122-123.

[19] Endothelial Cells; Studies from Peking University People's Hospital Reveal New Findings on Endothelial Cells (Atheroprotective effects of statins in patients with unstable angina by regulating the blood-borne micro RNA network). Biotech Week, 2017.

[20] Shariff M, Ashish Kumar U. Ample evidence for statins preloading before PCI on periprocedural myocardial infarction among stable angina pectoris patients undergoing percutaneous coronary intervention. Cardiovascular Revascularization Medicine, 2019,20(6).

[21] Weng Jing, Huang Yaqing, Yi Shiqing, et al. Effects of statins combined with isosorbide mononitrate on symptom improvement, electrocardiogram and blood lipid level in patients with angina pectoris of coronary heart disease. Knowledge of prevention and treatment of cardiovascular diseases (academic edition), 2019, 9(35):15-17.

[22] Jiang Hairui, Hao Liguo. Comparison of therapeutic effects of sodium tanshinone ⅡA sulfonate injection and Shuxuening injection on angina pectoris of coronary heart disease with qi deficiency and blood stasis. Chinese medicine guides, 2019, 16(01):145-148+152. 

[23] Tian Tian. Effect of metoprolol combined with sodium tanshinone ⅡA sulfonate on angina pectoris of coronary heart disease. Chinese Prescription Drugs, 2019,17(01):74-75. 

[24] Tian Wei. Clinical efficacy analysis of sodium tanshinone ⅡA sulfonate injection in treating angina pectoris of coronary heart disease. Modern Diagnosis and Treatment, 2019,30(05):727-729. 

[25] Zhao Hongxun. Effect of sodium tanshinone ⅡA sulfonate injection combined with esmolol on symptom improvement and ECG changes in patients with unstable angina pectoris. Capital Food and Medicine, 2019,26(08):76. 

[26] Li Xiaoyan. Effect of sodium tanshinone ⅡA sulfonate injection combined with nicorandil on symptom improvement and ECG changes in patients with angina pectoris of coronary heart disease. Capital Food and Medicine, 2019,26(23):87. 

[27] Shen Shu-jiao, Chi Miao-Miao, Wang Ying. Effect analysis of atorvastatin combined with sodium tanshinone IIA sulfonate in the treatment of angina pectoris of coronary heart disease. Famous Doctor, 2019,(12):246. 

[28] Su Ming. Sodium tanshinone ⅡA sulfonate and nicorandil in the treatment of angina pectoris of coronary heart disease. Clinical Application of Integrated Traditional Chinese and Western Medicine, 2019, 19(12):67-68. 

[29] Zhang Yonghong, Zhang Yan, Dong Huaqiong, et al. Clinical study of Wenxin granule combined with amlodipine in treating angina pectoris of coronary heart disease. Modern Medicine and Clinical, 2019, 34(05):1332-1336. 

[30] Luo Xinying. Clinical Observation of Compound Sanqi Humei Decoction in Treating Angina Pectoris of Coronary Heart Disease. Modern Diagnosis and Treatment, 2020, 31(12):1874-1875+1972.