Frontiers in Medical Science Research, 2022, 4(7); doi: 10.25236/FMSR.2022.040706.
Zheming Tang1, Shuo Wu2, Yinuo Wang3, Weiting Shen4
1Christ School, NY, USA
2China Jiliang University, Hangzhou, Zhejiang, China
3Northwestern Polytechnical University, Xi’an, Shaanxi, China
4Henan Polytechnic University, Jiaozuo, Henan, China
Among anticancer drugs, the research and development and preparation of nano drugs have always been the focus of current researchers, looking for appropriate molecular carriers that can make drugs play a better role. In this paper, PEG-DOX polymer was synthesized by using Poly(ethylene glycol) methyl ether (PEG-OH), 4-carboxybenzaldehyde, 4-(dimethyl-amino)-pyridine (DMAP), 1-(3-dimethylamino propyl)-3-ethyl carbodiimide hydrochloride (EDCI), triethylamine (TEA), hydrochloric acid, sodium sulfate, sodium bicarbonate, etc., through reasonable design and assembly, The stability, release behavior and antitumor activity of the drug were determined experimentally, to explore the best preparation scheme for the best effect of the drug.
peG-DOX nanoparticles, Nano drugs, Anticancer drugs
Zheming Tang, Shuo Wu, Yinuo Wang, Weiting Shen. Preparation of peG-DOX nanoparticles as nano drug carrier and treatment methods to achieve the best effect. Frontiers in Medical Science Research (2022) Vol. 4, Issue 7: 38-43. https://doi.org/10.25236/FMSR.2022.040706.
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