Zhi Zhang1, Zebin Zhang2, Xinxin Wang3, Yulong Li1
1Institute of Problem Solving, Shaanxi University of Chinese Medicine, Xianyang, China
2Shaanxi University of Chinese Medicine, Xianyang, China
3Northwest University, Xi'an, China
Liver cancer is one of the most common clinical malignant tumors, but the existing conventional chemotherapy drugs have low bioavailability, poor targeting, while killing cancer cells but also hurt the normal cells of the body, will seriously damage the body's immune system. Nanoparticles are used as drugs, protein, vaccines, nucleic acid fragments and other ideal carriers, widely used in biomedical research and clinical diagnosis and treatment, especially in the treatment of tumors, showing great application prospects. Polysaccharides are the polymer of monosaccharides. As natural biological materials, they are not only highly stable, hydrophilic, safe and non-toxic, but also easy to degrade in vivo. They are the most ideal material for the matrix carrier of nano-drug carrying system. In addition, because chitosan has good biocompatibility and no immunogenic properties on this basis, this paper studies the connection, influence and significance between chitosan nanoparticles and liver cancer based on the improvement of chitosan nanoparticles and the direction of targeted therapy.
Liver cancer; chitosan; nanoparticles; targeted therapy; bioavailability; drugs
Zhi Zhang, Zebin Zhang, Xinxin Wang, Yulong Li. Study on Chitosan Nanoparticles in Liver Cancer. Frontiers in Medical Science Research (2022) Vol. 4, Issue 8: 15-18. https://doi.org/10.25236/FMSR.2022.040804.
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