Frontiers in Medical Science Research, 2022, 4(10); doi: 10.25236/FMSR.2022.041010.
Qizhuo Hou1, Kongzhen Gu1,2
1Xiangya School of Medicine, Central South University, Changsha, 410031, Hunan, China
2Department of Laboratory Medicine, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China
Myelodysplastic syndromes (MDS) are a group of acquired heterogeneous clonal disorders that originate from hematopoietic stem cells. It is characterized by a reduction in one or more blood lines in the myeloid system with abnormal development, pathological hematopoiesis and a high risk of transformation to acute myeloid leukemia (AML). In 2016, the World Health Organization (WHO) revised the diagnostic staging criteria for MDS, but with the development of next-generation sequencing (NGS) technology, the diagnostic staging of MDS has opened a new era of accurate diagnosis and individualized treatment. In this paper, we review the diagnostic typing of MDS.
Myelodysplastic syndrome; diagnostic typing; next-generation sequencing technology; precise diagnosis
Qizhuo Hou, Kongzhen Gu. Progress in diagnostic staging of myelodysplastic syndrome. Frontiers in Medical Science Research (2022) Vol. 4, Issue 10: 56-61. https://doi.org/10.25236/FMSR.2022.041010.
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