Macrophages are one of the important innate immune cells in human body. Phenotypic variability and functional diversity are important characteristics of macrophages, which can be polarized under the induction and regulation of different microenvironmental signals. After polarization, macrophages further affect the local immune response, and cooperate with various cytokines in pathogen and microbial infection, tumor and immune regulation, tissue remodeling and regulation. Therefore, the polarization of macrophages and their role after polarization have become a new research hotspot.  

Shangyi Lv, Lisha Ma, Huiyu He. Research status of macrophage polarization and osteogenesis and vasculogenesis after polarization. Frontiers in Medical Science Research (2022) Vol. 4, Issue 11: 47-52. https://doi.org/10.25236/FMSR.2022.041108.

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