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Frontiers in Medical Science Research, 2022, 4(11); doi: 10.25236/FMSR.2022.041108.

Research status of macrophage polarization and osteogenesis and vasculogenesis after polarization


Shangyi Lv1,2, Lisha Ma1,2, Huiyu He1,2

Corresponding Author:
Huiyu He

1Department of Prosthodontics and Dental Implantology, The First Affiliated Hospital of Xinjiang Medical University (Affiliated Stomatological Hospital), Urumqi, Xinjiang, 830054, China

2Xinjiang Uygur Autonomous Region Institute of Stomatology, Urumqi, Xinjiang, 830054, China


Macrophages are one of the important innate immune cells in human body. Phenotypic variability and functional diversity are important characteristics of macrophages, which can be polarized under the induction and regulation of different microenvironmental signals. After polarization, macrophages further affect the local immune response, and cooperate with various cytokines in pathogen and microbial infection, tumor and immune regulation, tissue remodeling and regulation. Therefore, the polarization of macrophages and their role after polarization have become a new research hotspot.  


Macrophages, Polarization, Osteogenesi, Angiogenesis

Cite This Paper

Shangyi Lv, Lisha Ma, Huiyu He. Research status of macrophage polarization and osteogenesis and vasculogenesis after polarization. Frontiers in Medical Science Research (2022) Vol. 4, Issue 11: 47-52. https://doi.org/10.25236/FMSR.2022.041108.


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