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Frontiers in Medical Science Research, 2023, 5(2); doi: 10.25236/FMSR.2023.050202.

Brief description of the synthesis of new nitrogen oxides


Yingjie Hou1, Ping Li1, Jianing Li2

Corresponding Author:
Yingjie Hou

1Pharmacy, North China University of Science and Technology, Tangshan, China

2Pharmaceutical Preparation, North China University of Science and Technology, Tangshan, China


Cancer is one of the major diseases that endanger human life and health. Common anticancer drugs have high side effects and are prone to drug resistance, leading to treatment failure. Due to their special structures and lipophilicity, cage compounds have more pharmacological activities in their derivatives, such as antiviral, immune enhancing, and antitumor activities. Scientists have used cage compounds with good lipophilicity as structural units to develop new drugs with good selectivity, high efficiency and low toxicity. nIT-like nitroxide radicals have excellent antitumor activity, and this paper reviews the investigation of introducing cage structures into NIT-like nitroxide radicals to design and synthesize novel nitrogen oxides.


cancer, caged compounds, nitrogen-oxygen radicals, novel nitrogen oxides

Cite This Paper

Yingjie Hou, Ping Li, Jianing Li. Brief description of the synthesis of new nitrogen oxides. Frontiers in Medical Science Research (2023) Vol. 5, Issue 2: 9-12. https://doi.org/10.25236/FMSR.2023.050202.


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