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Frontiers in Medical Science Research, 2023, 5(2); doi: 10.25236/FMSR.2023.050204.

Research progress of Chinese medicine in the treatment of HyCoSy diagnosis of infertility


Qing Cheng1, Xiaomao Liu2

Corresponding Author:
Xiaomao Liu

1Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi, China

2Yulin Hospital of Traditional Chinese Medicine, Yulin, 719051, Shaanxi, China


Infertility is defined as having sex without contraception for more than 12 months without becoming pregnant. The incidence of infertility is high. Once the disease occurs, it will not only affect the physical and mental health of women, but also affect the harmony of their families. Fallopian tube obstruction is the main factor causing infertility. In the past, X-ray hysterosalpingography was used to evaluate the patency of fallopian tube. In recent years, contrast-enhanced ultrasound technology has become more and more mature. It has the advantages of safety, accuracy, non-invasive, and reproducibility in evaluating fallopian tube patency, and is conducive to real-time observation of uterine cavity morphology, which has been widely used in the diagnosis and treatment of infertility. To evaluate the efficacy of Hysterosalpingo contrast sonography (Hysterosalpingo contrast sonography, hysterosalpingo contrast sonography, hysterosalpingo contrast sonography, hysterosalpingo contrast sonography, The improvement of adverse reactions such as pain caused by HyCoSy) in the diagnosis of infertility, and whether there are significant differences in the benefits brought by Hycosy compared with single moxa salt pack hot compress and conventional drugs for pain relief. This article reviews the research progress of Chinese and western medicine related to HyCoSy in the diagnosis of infertility in recent years, so as to provide some reference for clinicians.


Hysterosalpingography; Infertility; Etiology and pathogenesis; Traditional Chinese and western medicine; Review

Cite This Paper

Qing Cheng, Xiaomao Liu. Research progress of Chinese medicine in the treatment of HyCoSy diagnosis of infertility. Frontiers in Medical Science Research (2023) Vol. 5, Issue 2: 24-30. https://doi.org/10.25236/FMSR.2023.050204.


[1] Liu Li, Zhao Junli. Emotion and coping style of infertility patients of different genders [J]. Chinese Journal of Mental Health, 2011, 25(11):806-809

[2] Zhang H, Wang S, Zhang S, et al. Increasing trend of prevalence of infertility in Beijing[J]. Chin J Med (English edition), 2014, 127(4).

[3] Zhou L, Zhang X, Chen X, et la. Value of three-dimensional.tysterosalpingo-contrast sonography with SonoVue in the assessment oftubal patency[J].Ultrasound Obstet Gynecol. 2012, 40 (1) : 93-98.

[4] Zhang X, Li Y F, Cui C Y,etal. Relationship between fertility stress and general self-efficacy and anxiety in female infertility patients [J]. China Public Health,2019: 807-809.

[5] Newton CR, Sherrard W, Glavac I. The Fertility Problem Inventory: measuring perceived infertility-related stress[J]. Fertil Steril, 1999, 72(1): 54-62.

[6] Lian Fang, 2017.6, TCM Gynecology, Science Press,336 pp.

[7] Giuseppe Lo Monte, Gianpiero Capobianco, Isabella Piva, Donatella Caserta, Salvatore Dessole, Roberto Marci.,Hysterosalpingo contrast sonography (HyCoSy): let's make the point! [J]. Archives of Gynecology and Obstetrics,2015,291(1):

[8] Qiang Ye,Mao Shu Xia,Wu Yi Yun,Li Hong Bo,Cai Ting.Effect of transvaginal real-time three-dimensional hysterosalpingo-contrast-enhanced ultrasound in the treatment of infertility [J]. Chinese Journal of Family Planning and Obstetrics and Gynecology, 2019,11(10):68-70+83.

[9] Cui Qi,Liang Xi,Li Ying.Clinical value of four-dimensional hysterosalpingo-contrast-enhanced ultrasound in pre-pregnancy screening of assisted reproductive technology [J]. Chin J Medical Ultrasound (Electronic Edition), 2020: 1103-1107.

[10] Salata I, Gottwald L, Sobkiewicz S. [Comparison of assessing the patency of the Fallopian tubes during laparoscopy and during hysterosalpingography on television in infertile women with endometriosis].[J]. Ginekologia Polska, 2003, 74(9):1014.

[11] Jain T. Socioeconomic and racial disparities among infertility patients seeking care[J]. Fertility & Sterility, 2006, 85(4):876-881.

[12] F Chen, Quan J, Huang P, et al. Hysterosalpingo-Contrast Sonography With Four-Dimensional Technique for Screening Fallopian Tubal Patency:,Let's Make an Exploration[J]. Journal of Minimally Invasive Gynecology, 2016, 24(3):407-414.

[13] Wang W, Zhou Q, Gong Y, Li Y, Huang Y,,Chen Z. Assessment of Fallopian Tube Fimbria Patency With 4-Dimensional Hysterosalpingo-Contrast Sonography in Infertile,Women. J Ultrasound Med. 2017. Oct; 36(10):2061-2069. doi: 10.1002/ jum. 14244. Epub 2017 May 24. PMID: 28543598.

[14] Xiang Yuting, Bai Wenpei. Clinical application of ultrasound imaging in diagnosis of tubal patency [J]. International Journal of Reproductive Health/Family Planning, 2016, 35(2):4.

[15] Wang Xiaoqian, SUN Zhiwei, Wang Lin, et al. Analysis of the tolerance and pain factors of transvaginal real-time three-dimensional hysterosalpingo-contrast-enhanced ultrasound [J]. J Clinical Ultrasound Med, 2018, 20(6):417-419.

[16] Zhang Xinxin. Effect of modified Guishen pill on infertility with decreased ovarian reserve function of kidney deficiency [J]. Chinese Medicine Guide, 2018, 16(14):2.

[17] Wang Zhuan, Lin Kuang-Jilin. Self-made Bushen Tongluo decoction combined with artificial cycle in the treatment of infertility caused by decreased ovarian reserve function [J]. Chin J Clin Med, 2020, 32(3):486-489.