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Frontiers in Medical Science Research, 2023, 5(2); doi: 10.25236/FMSR.2023.050206.

Progress in application of natural scaffold materials in pulp regeneration


Dujuan Yang1, Mengke Cheng1, Yulu Zhang1, Jia Liu1,2

Corresponding Author:
Jia Liu

1Department of Pediatric Dentistry-Preventive Stomatology, The first Affiliated Hospital (Affiliated Stomatological Hospital) of Xinjiang Medical University, Xinjiang Uygur Autonomous Region, China

2Institute of Stomatology, Urumqi, Xinjiang Uygur Autonomous Region, China


Endodontic and periapical diseases are two of the most common oral diseases and usually cause irreversible damage to the pulp due to severe irritation, such as dental caries, accidental trauma, or iatrogenic causes. The typical dental pulp treatment method is root canal therapy, but the loss of dental pulp tissue changes the function of dental pulp, and may cause a series of complications. Pulp regeneration therapy uses the principle of tissue engineering to replace the diseased pulp tissue with new pulp tissue so as to achieve the purpose of restoring the normal physiological function of the pulp. Scaffolds are one of the important elements of tissue engineering, and a variety of scaffolds have been found to potentially be used in pulp regeneration. Naturally derived scaffold materials have good biocompatibility and rapid degradation rate and are widely used in endodontic tissue engineering.


Scaffold materials; Dental pulp stem cells; Pulp regeneration

Cite This Paper

Dujuan Yang, Mengke Cheng, Yulu Zhang, Jia Liu. Progress in application of natural scaffold materials in pulp regeneration. Frontiers in Medical Science Research (2023) Vol. 5, Issue 2: 37-42. https://doi.org/10.25236/FMSR.2023.050206.


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