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Frontiers in Medical Science Research, 2023, 5(2); doi: 10.25236/FMSR.2023.050215.

Research progress of local sustained-release drug delivery system in the treatment of peri-implantitis


Yijing Cao1, Wenjie Zhang1, Suiyan Wei1, Guoqiang Xu1

Corresponding Author:
Guoqiang Xu

1The First Affiliated Hospital of Xinjiang Medical University (Affiliated Stomatological Hospital), Urumqi, Xinjiang Uygur Autonomous Region, 830054, China


With the increasing demand for oral implants, the incidence of peri-implantitis is also increasing year by year, and serious cases may even lead to implant loss. Studies have shown that the clinical treatment of peri-implantitis is divided into resection and regenerative surgery, and conventional drug treatment is divided into systemic and local administration. Compared with systemic administration, the local sustained-release system can not only reduce the adverse reactions and drug resistance of systemic administration, but also achieve a high concentration of drugs that can continuously kill bacteria in the periodontal pocket. Therefore, the treatment of peri-implantitis with local sustained-release system has become a research hotspot at home and abroad. This article reviews the research progress of local sustained-release system in the treatment of peri-implantitis in recent years.


material, peri-implantitis, local drug-loaded sustained-release materials

Cite This Paper

Yijing Cao, Wenjie Zhang, Suiyan Wei, Guoqiang Xu. Research progress of local sustained-release drug delivery system in the treatment of peri-implantitis. Frontiers in Medical Science Research (2023) Vol. 5, Issue 2: 89-93. https://doi.org/10.25236/FMSR.2023.050215.


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